特异性
This antibody detects endogenous levels of CD3E
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
来源
Monoclonal, Rabbit,IgG
稀释比例
Ready to use for IHC Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
纯化工艺
Recombinant Expression and Affinity purified
储存
2°C to 8°C/1 year,Ship by ice bag
其他名称
4930549J05Rik ; A430104F18Rik ; AW552088 ; Cd247 ; CD247 antigen ; CD247 antigen, zeta subunit ; CD247 molecule ; CD3 ; CD3 antigen, delta subunit ; CD3 delta ; CD3 epsilon ; CD3 eta ; CD3 gamma ; CD3 molecule delta polypeptide ; CD3 molecule, epsilon polypeptide ; CD3 molecule, gamma polypeptide ; CD3 zeta ; CD3-DELTA ; CD3d ; CD3D antigen delta polypeptide ; CD3d antigen, delta polypeptide ; TiT3 complex ; CD3d molecule delta ; CD3d molecule delta CD3 TCR complex ; CD3d molecule, delta ; CD3-TCR complex ; CD3D_HUMAN ; CD3E ; CD3e antigen ; CD3E antigen epsilon polypeptide ; CD3e antigen, epsilon polypeptide ; TiT3 complex ; CD3e molecule epsilon ; CD3e molecule epsilon CD3 TCR complex ; CD3e molecule, epsilon ; CD3-TCR complex ; CD3epsilon ; CD3G ; CD3g antigen ; CD3G antigen gamma polypeptide ; CD3g antigen, gamma polypeptide ; TiT3 complex ; CD3g molecule gamma ; CD3g molecule gamma CD3 TCR complex ; CD3g molecule, gamma ; CD3-TCR complex ; CD3H ; CD3Q ; CD3Z ; CD3zeta ; Ctg3 ; FLJ17620 ; FLJ17664 ; FLJ18683 ; FLJ79544 ; FLJ94613 ; IMD19 ; Leu-4 ; MGC138597 ; OKT3, delta chain ; OTTHUMP00000032544 ; T cell receptor ; T cell receptor T3 delta chain ; T cell receptor T3 gamma chain ; T cell receptor T3 zeta chain ; T cell receptor zeta chain ; T cell surface antigen T3/Leu 4 epsilon chain ; T cell surface glycoprotein CD3 ; T cell surface glycoprotein CD3 delta chain ; T cell surface glycoprotein CD3 epsilon chain ; T cell surface glycoprotein CD3 gamma chain ; T cell surface glycoprotein CD3 zeta chain ; T-cell antigen receptor complex, delta subunit of T3 ; T-cell antigen receptor complex, epsilon subunit of T3 ; T-cell antigen receptor complex, gamma subunit of T3 ; T-cell antigen receptor complex, zeta subunit of CD3 ; T-cell receptor T3 delta chain ; T-cell receptor T3 gamma chain ; T-cell surface antigen T3/Leu-4 epsilon chain ; T-cell surface glycoprotein CD3 delta chain ; T-cell surface glycoprotein CD3 epsilon chain ; T-cell surface glycoprotein CD3 gamma chain ; T3 ; T3d ; T3e ; T3g ; T3z ; TCRE ; TCRk ; Tcrz ; TCRzeta
背景
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008],
功能
The CD3 complex mediates signal transduction.,online information:CD3E mutation db,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 1 ITAM domain.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.,
