分子量(DA)
Calculated MW: 54 kDa; Observed MW: 54 kDa
免疫原
A synthesized peptide derived from human MLKL
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100
储存
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
背景
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma
membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane
damage. Does not have protein kinase activity.