蛋白名称
Meiotic recombination protein DMC1/LIM15 homolog
免疫原
The specific immunogen used to produce this antibody is proprietary information.
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
DMC1;Meiotic recombination protein DMC1/LIM15 homolog;DMC1 ;
DMC1H ;
LIM15 ;
Meiotic recombination protein DMC1/LIM15 homolog
背景
DNA meiotic recombinase 1 (DMC1) Homo sapiens This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins) . Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein , which is evolutionarily conserved , is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq , May 2013] ,
功能
Function:May participate in meiotic recombination , specifically in homologous strand assimilation , which is required for the resolution of meiotic double-strand breaks. ,similarity:Belongs to the recA family. DMC1 subfamily. ,similarity:Contains 1 HhH domain. ,subunit:Interacts with the MND1-PSMC3IP heterodimer (By similarity) . Double stacked ring-shaped homooctamer. ,
