免疫原
The specific immunogen used to produce this antibody is proprietary information.
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
"IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000 Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)"
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
背景
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family , which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency , leading to nonketotic hypoglycemia. [provided by RefSeq , Jul 2008] ,
功能
Catalytic activity:Acyl-CoA + acceptor = 2 ,3-dehydroacyl-CoA + reduced acceptor. ,cofactor:FAD. ,Disease:Impaired ACADL activity results in non-ketotic hypoglycemia , hypotonia , muscle weakness and episodes of cardiorespiratory arrest associated with fasting [MIM:201460]. ,miscellaneous:A number of straight-chain acyl-CoA dehydrogenases of different substrate specificities are present in mammalian tissues. ,pathway:Lipid metabolism; mitochondrial fatty acid beta-oxidation. ,similarity:Belongs to the acyl-CoA dehydrogenase family. ,subunit:Homotetramer. ,
