蛋白名称
Parathyroid hormone (Parathormone) (Parathyrin)
特异性
This antibody detects endogenous levels of Parathyroid Hormone
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
来源
Monoclonal, Rabbit,IgG
稀释比例
Ready to use for IHC Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
纯化工艺
Recombinant Expression and Affinity purified
储存
2°C to 8°C/1 year,Ship by ice bag
其他名称
hPTH ; PaRathormone ; PaRathyrin ; PaRathyroid hormone 1 ; PaRathyroid hormone ; Prepro PTH ; PrepropaRathyroid hormone ; PTH ; PTH1 ; PTH1 receptor ; PTH1R ; PTHR ; PTHR1 ; PTHY_HUMAN
背景
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
功能
Disease:Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.,Function:PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.,online information:Parathyroid hormone entry,similarity:Belongs to the parathyroid hormone family.,
