特异性
This antibody detects endogenous levels of CD99
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
来源
Monoclonal, Rabbit,IgG
稀释比例
Ready to use for IHC Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
纯化工艺
Recombinant Expression and Affinity purified
储存
2°C to 8°C/1 year,Ship by ice bag
其他名称
12E7 ; Antigen identified by monoclonal 12E7, Y homolog ; Antigen identified by monoclonal antibodies 12E7, F21 and O13 ; CD99 ; Cell surface antigen 12E7 ; Cell surface antigen HBA 71 ; Cell surface antigen O13 ; E2 antigen ; HBA71 ; MIC 2X ; MIC 2Y ; MIC2 ; MIC2X ; MIC2Y ; MSK5X ; Protein MIC2 ; Surface antigen MIC2 ; T cell surface glycoprotein E2
背景
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016],
功能
Involved in T-cell adhesion processes. It is involved in spontaneous rosette formation with erythrocytes.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,PTM:Extensively O-glycosylated.,similarity:Belongs to the CD99 family.,
