蛋白名称
Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleaved into: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form]
特异性
This antibody detects endogenous levels of CD23
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
来源
Monoclonal, Rabbit,IgG
稀释比例
Ready to use for IHC Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
纯化工艺
Recombinant Expression and Affinity purified
储存
2°C to 8°C/1 year,Ship by ice bag
其他名称
Blast 2 ; BLAST-2 ; Blast2 ; C type lectin domain family 4 member J ; C-type lectin domain family 4 ; C-type lectin domain family 4 member J ; C-type lectin domain family 4, member J ; CD 23 ; CD 23A ; CD23 ; CD23 antigen ; CD23A ; CLEC 4J ; CLEC4J ; Fc epsilon receptor II ; Fc epsilon RII ; Fc fragment of IgE ; Fc fragment of IgE low affinity II receptor for ; Fc fragment of IgE receptor II ; Fc fragment of IgE, low affinity II, receptor for ; CD23 ; Fc of IgE ; Fc of IgE, low affinity II, receptor for ; CD23 ; Fc receptor IgE low affinity II alpha polypeptide ; Fc receptor, IgE, low affinity II, alpha polypeptide, isoform CRA_a ; Fc-epsilon-RII ; FCE 2 ; FCE2 ; FCER 2 ; Fcer2 ; FCER2_HUMAN ; FCER2A ; FceRII ; IgE binding factor ; IgE receptor lymphocyte ; IgE-binding factor ; IGEBF ; Immunoglobulin E binding factor ; Immunoglobulin E receptor ; Immunoglobulin E receptor, low affinity II ; Immunoglobulin E-binding factor ; Immunoglobulin epsilon chain ; LEUKOCYTE ANTIGEN CD23 ; Low Affinity IgE Receptor ; Low affinity immunoglobulin epsilon Fc receptor ; Low affinity immunoglobulin epsilon Fc receptor membrane bound form ; Low affinity immunoglobulin epsilon Fc receptor soluble form ; Ly-42 ; Ly42 ; Lymphocyte antigen CD23 ; Lymphocyte IgE receptor ; MGC93219
背景
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],
功能
This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).,miscellaneous:There are two kinds of Fc receptors for IgE, which differ in both structure and Function: high affinity receptors on basophils and mast cells and low affinity receptors on lymphocytes and monocytes.,online information:CD23,PTM:N- and O-glycosylated.,similarity:Contains 1 C-type lectin domain.,subcellular location:Also exists as a soluble excreted form.,
