组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
Fatty acid-binding protein, adipocyte ; Adipocyte lipid-binding protein ; ALBP ; Adipocyte-type fatty acid-binding protein ; A-FABP ; AFABP ; Fatty acid-binding protein 4 ;
背景
FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008],
功能
Domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,Function:Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,subcellular location:Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.,subunit:Homodimer. Interacts with PPARG (By similarity). Monomer.,