组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
NT5E ; NT5 ; NTE ; 5'-nucleotidase ; 5'-NT ; Ecto-5'-nucleotidase ; CD73
背景
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011],
功能
Catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Zinc.,Disease:There is a decrease in the activity of NT5 in B-cell chronic lymphocytic leukemia.,Function:Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.,similarity:Belongs to the 5'-nucleotidase family.,subunit:Homodimer; disulfide-linked.,
