蛋白名称
Golgin subfamily A member 2
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein ; GM130 ; GM130 autoantigen ; Golgin-95)
背景
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids inThe secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions betweenThe Golgi and microtubules are thought to be important forThe reorganization ofThe Golgi after it fragments during mitosis. This gene encodes one ofThe golgins, a family of proteins localized toThe Golgi. This encoded protein has been postulated to play roles inThe stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, butThe full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010],
功能
Domain:Extended rod-like protein with coiled-coil domains.,Function:Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.,sequence Caution:Sequence differs from that shown after position 814 due to an internal deletion.,similarity:Belongs to the GOLGA2 family.,subunit:Part of a larger oligomeric complex. Interacts with p115 (By similarity). Interacts with RAB1B that has been activated by GTP-binding. Interacts with GORASP1/GRASP65 and ZFPL1.,