基因名称(Gene Name)
ACTR1B;CTRN2
蛋白名称
Beta-centractin;Actin-related protein 1B;ARP1B;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
WB 1:1000-5000; IHC 1:100-300; ICC/IF 1:100-300; FC 1:100-300; IP 1:50-100 Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
ACTR1B ; CTRN2 ; Beta-centractin ; Actin-related protein 1B ; ARP1B ;
背景
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008],
功能
Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.
