基因名称(Gene Name)
BCAS1;AIBC1;NABC1
蛋白名称
Breast carcinoma-amplified sequence 1;Amplified and overexpressed in breast cancer;Novel amplified in breast cancer 1;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
BCAS1 ; AIBC1 ; NABC1 ; Breast carcinoma-amplified sequence 1 ; Amplified and overexpressed in breast cancer ; Novel amplified in breast cancer 1 ;
背景
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016]
功能
Required for myelination. {ECO:0000250|UniProtKB:Q80YN3}.
