基因名称(Gene Name)
NFKBIE;IKBE
蛋白名称
NF-kappa-B inhibitor epsilon;NF-kappa-BIE;I-kappa-B-epsilon;IkB-E;IkB-epsilon;IkappaBepsilon;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
WB 1:1000-5000; IHC 1:100-300; ICC/IF 1:100-300; IP 1:50-100 Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
NFKBIE ; IKBE ; NF-kappa-B inhibitor epsilon ; NF-kappa-BIE ; I-kappa-B-epsilon ; IkB-E ; IkB-epsilon ; IkappaBepsilon ;
背景
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011],
功能
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes. {ECO:0000269|PubMed:9315679}.
