蛋白名称
Interferon-inducible protein AIM2
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
AIM2 ; Interferon-inducible protein AIM2 ; Absent in melanoma 2
背景
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008],
功能
Disease:Defects in AIM2 may be a cause of microsatellite unstable colon cancers.,Function:Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.,induction:By interferon gamma.,similarity:Belongs to the HIN-200 family.,similarity:Contains 1 DAPIN domain.,similarity:Contains 1 HIN-200 domain.,subunit:Homodimer.,tissue specificity:Expressed in spleen, small intestine, peripheral blood leukocytes, and testis.,
