蛋白名称
C-X-C chemokine receptor type 7
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
CXCR7 ; CMKOR1 ; GPR159 ; RDC1 ; C-X-C chemokine receptor type 7 ; CXC-R7 ; CXCR-7 ; Chemokine orphan receptor 1 ; G-protein coupled receptor 159 ; G-protein coupled receptor RDC1 homolog ; RDC-1
背景
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008],
功能
Caution:Was originally (PubMed:1675791) thought to be the receptor for VIP.,Function:Receptor for CXCL12/SDF1. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.,online information:CXC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in monocytes, basophils, and B-cells. Lower expression in CD4+ T-lymphocytes and natural killer cells.,
