基因名称(Gene Name)
GABARAP GABARAPL1 GABARAPL2
蛋白名称
Gamma-aminobutyric acid receptor-associated protein;Gamma-aminobutyric acid receptor-associated protein-like 1;Gamma-aminobutyric acid receptor-associated protein-like 2
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
来源
Monoclonal, Rabbit,IgG
稀释比例
IHC 1:1000-1:4000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
FLC3B,HT004,GEC1,FLC3A,GEF2,GABA(A) receptor-associated protein,GABA(A) receptor-associated protein-like 1,GABA(A) receptor-associated protein-like 2,
背景
Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008],
功能
May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.,similarity:Belongs to the MAP1 LC3 family.,subcellular location:Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules.,subunit:Interacts with GPHN and NSF (By similarity). Interacts with GABRG2, beta-tubulin and ULK1.,tissue specificity:Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.,
