基因名称(Gene Name)
ESYT2 FAM62B KIAA1228
蛋白名称
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
免疫原
Synthesized peptide derived from human FAM62B. AA range:786-856
特异性
This antibody detects endogenous levels of FAM62B at Human, Mouse,Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
ESYT2 FAM62B KIAA1228;Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
功能
Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) .