基因名称(Gene Name)
ATAD1 FNP001
蛋白名称
ATPase family AAA domain-containing protein 1 (Thorase)
免疫原
Synthesized peptide derived from human ATAD1. AA range:120-190
特异性
This antibody detects endogenous levels of ATAD1 at Human, Mouse,Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
ATAD1 FNP001;ATPase family AAA domain-containing protein 1 (Thorase)
功能
Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria . Specifically recognizes and binds tail-anchored transmembrane proteins: acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane (By similarity) . Also plays a critical role in regulating the surface expression of AMPA receptors (AMPAR) , thereby regulating synaptic plasticity and learning and memory (By similarity) . Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (By similarity) .
