基因名称(Gene Name)
SH3BP5 SAB
蛋白名称
SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK)
免疫原
Synthesized peptide derived from human SH3BP5. AA range:272-372
特异性
This antibody detects endogenous levels of SH3BP5 at Human, Mouse,Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
SH3BP5 SAB;SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK)
功能
Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 . Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
