背景
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares
similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in
homologous recombination and repair of DNA.This protein binds to double-stranded DNA,
and displays ATPase activity in the presence of DNA.This gene is highly expressed in testis
and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous
mutations of this gene were observed in primary lymphoma and colon cancer.
