蛋白名称
Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP)
免疫原
Synthesized peptide derived from human COPG2. AA range:407-477
特异性
This antibody detects endogenous levels of COPG2 at Human, Mouse,Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
COPG2;Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP)
功能
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles , which further mediate biosynthetic protein transport from the ER , via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes , and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals , the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs) , which are small GTP-binding proteins; the complex also influences the Golgi structural integrity , as well as the processing , activity , and endocytic recycling of LDL receptors (By similarity) .
