免疫原
Synthetic peptide.This information is considered to be commercially sensitive.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
GT; GT1; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93; CD41/ITGA2B
背景
This gene encodes a member of the integrin alpha chain family of proteins.The encoded
preproprotein is proteolytically processed to generate light and heavy chains that associate
through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion
receptor.This receptor plays a crucial role in the blood coagulation system, by mediating
platelet aggregation. Mutations in this gene are associated with platelet-type bleeding
disorders, which are characterized by a failure of platelet aggregation, including Glanzmann
thrombasthenia.