基因名称(Gene Name)
PDXP CIN PLP PLPP
蛋白名称
Pyridoxal phosphate phosphatase (PLP phosphatase) (Chronophin)
免疫原
Synthesized peptide derived from human PDXP. AA range:42-112
特异性
This antibody detects endogenous levels of PDXP at Human, Mouse,Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
PDXP CIN PLP PLPP;Pyridoxal phosphate phosphatase (PLP phosphatase) (Chronophin)
功能
Functions as a pyridoxal phosphate (PLP) phosphatase , which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP) , with order of substrate preference PLP > PNP > PMP and therefore plays a role in vitamin B6 metabolism . Also functions as a protein serine phosphatase that specifically dephosphorylates 'Ser-3' in proteins of the actin-depolymerizing factor (ADF) /cofilin family like CFL1 and DSTN. Thereby , regulates cofilin-dependent actin cytoskeleton reorganization , being required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phosphothreonines in LIMK1. Does not dephosphorylate peptides containing phosphotyrosine .
