基因名称(Gene Name)
FANCI KIAA1794
蛋白名称
Fanconi anemia group I protein (Protein FACI)
免疫原
Synthesized peptide derived from human FANCI. AA range:678-778
特异性
This antibody detects endogenous levels of FANCI at Human, Mouse,Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
FANCI KIAA1794;Fanconi anemia group I protein (Protein FACI)
功能
Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) . Participates in S phase and G2 phase checkpoint activation upon DNA damage.
