免疫原
Recombinant protein (or fragment).This information is considered to be commercially
sensitive.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
其他名称
PBP; CRSP1; RB18A;TRIP2; PPARBP; CRSP200; DRIP205; DRIP230; PPARGBP;TRAP220; MED1
背景
The activation of gene transcription is a multistep process that is triggered by factors that
recognize transcriptional enhancer sites in DNA.These factors work with co-activators to
direct transcriptional initiation by the RNA polymerase II apparatus.The protein encoded by
this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which,
along with TFIID, is required for efficient activation by SP1 .This protein is also a component
of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins
which interact with TR and facilitate TR function on DNA templates in conjunction with
initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential
for adipogenesis.This protein is known to have the ability to self-oligomerize.
