背景
This gene is a type I subclass member of the Reg gene family. The Reg gene family is a
multigene family grouped into four subclasses, types I, II, III and IV, based on the primary
structures of the encoded proteins. This gene encodes a protein that is secreted by the
exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may
be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene
are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral
gene by gene duplication.
