背景
This gene product is a member of the serine-arginine (SR) family of proteins, which are
involved in constitutive and regulated RNA splicing. Members of this family are characterized
by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple Cterminal SR/RS repeats, which are important in mediating association with other cellular
proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS
on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14,
18, and 20. Alternative splicing results in multiple transcript variants.
