免疫原
Recombinant protein (or fragment).This information is considered to be commercially
sensitive.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
HMN5; PELD; HMN5C; SPG17; GNG3LG; BSCL2
背景
This gene encodes the multi-pass transmembrane protein protein seipin. This protein
localizes to the endoplasmic reticulum and may be important for lipid droplet morphology.
Mutations in this gene have been associated with congenital generalized lipodystrophy type
2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near
absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript
variants encoding different isoforms have been found for this gene. Naturally occurring readthrough transcription occurs between this locus and the neighboring locus HNRNPUL2
(heterogeneous nuclear ribonucleoprotein U-like 2).
