基因名称(Gene Name)
TRIM26 RNF95 ZNF173
蛋白名称
Tripartite motif-containing protein 26 (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173)
免疫原
Synthesized peptide derived from human TRIM26
特异性
This antibody detects endogenous levels of TRIM26 at Human, Mouse,Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
