背景
The protein encoded by this gene is a member of the S100 family of proteins containing 2
EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus
of a wide range of cells, and involved in the regulation of a number of cellular processes
such as cell cycle progression and differentiation. S100 genes include at least 13 members
which are located as a cluster on chromosome 1q21. This protein may function in motility,
invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression
of this gene have been implicated in tumor metastasis.
