免疫原
Synthetic peptide. This information is considered to be commercially sensitive.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
MULE; Ib772; LASU1; MRXST; UREB1; HECTH9; URE-B1; ARF-BP1; HSPC272; HUWE1
背景
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein
ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for
the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid
cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor
suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated
with Turner type X-linked syndromic cognitive disability
