蛋白名称
Crossover junction endonuclease MUS81 (EC 3.1.22.-)
免疫原
Synthesized peptide derived from human MUS81
特异性
This antibody detects endogenous levels of MUS81 at Human, Mouse,Rat
组成
This antibody detects endogenous levels of MUS81 at Human, Mouse,Rat
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. Plays an essential role in mitosis for the processing of stalled or collapsed replication forks .
