免疫原
Recombinant protein (or fragment).This information is considered to be commercially
sensitive.
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
RNH1; H1RNA; PEOB2; RNASEH1
背景
This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids
and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation
results in the production of alternate isoforms that are directed to the mitochondria or to the
nucleus. The production of the mitochondrial isoform is modulated by an upstream open
reading frame (uORF). Mutations in this gene have been found in individuals with
progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal
recessive 2. Alternative splicing results in additional coding and non-coding transcript
variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17.
