免疫原
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human E2F3
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
背景
This gene encodes a member of a small family of transcription factors that function through
binding of DP interaction partner proteins. The encoded protein recognizes a specific
sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to
regulate the expression of genes involved in the cell cycle. Altered copy number and activity
of this gene have been observed in a number of human cancers. There are pseudogenes for
this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript
variants
