背景
This gene encodes a member of the multiple epidermal growth factor-like domains protein
family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a
critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the
brain. Expression of this gene may be associated with schizophrenia, and mutations in this
gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia
(EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript
variants have been observed for this gene
