免疫原
A phospho specific peptide corresponding to residues surrounding Y1173 of human EGFR
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
ERBB; ERRP; HER1; mENA; ERBB1; PIG61; NISBD2; Phospho-EGFR-Y1173
背景
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the
protein kinase superfamily. This protein is a receptor for members of the epidermal growth
factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus
inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation.
Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine
storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting
from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
