免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 208-457 of
human NFS1 (NP_066923.3).
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
IscS; NIFS; COXPD52; HUSSY-08; NFS1
背景
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins
encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from
cysteine, creating alanine in the process. This gene uses alternate in-frame translation
initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of
the alternative initiation sites is determined by the cytosolic pH. The encoded proteins
belong to the class-V family of pyridoxal phosphate-dependent aminotransferases.
Alternatively spliced transcript variants have been described.
