免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-314 of
human CRYM (NP_001879.1)
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
背景
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is
also called phylogenetically-restricted crystallins. The latter class constitutes the major
proteins of vertebrate eye lens and maintains the transparency and refractive index of the
lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has
sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not
perform a structural role in lens tissue, and instead it binds thyroid hormone for possible
regulatory or developmental roles. Mutations in this gene have been associated with
autosomal dominant non-syndromic deafness.
