免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 216-485 of
human POLG2 (NP_009146.2).
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
HP55; POLB; PEOA4; POLGB; MTPOLB; MTDPS16; MTDPS16A; MTDPS16B; POLG-BETA; POLG2
背景
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma.
The encoded protein forms a heterotrimer containing one catalytic subunit and two
processivity subunits. This protein enhances DNA binding and promotes processive DNA
synthesis. Mutations in this gene result in autosomal dominant progressive external
ophthalmoplegia with mitochondrial DNA deletions
