免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 204-463 of
human DLC1 (NP_079043.3).
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
其他名称
HP; ARHGAP7; STARD12; p122-RhoGAP; DLC1
背景
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family
of proteins which play a role in the regulation of small GTP-binding proteins. GAP family
proteins participate in signaling pathways that regulate cell processes involved in
cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of
common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript
variants due to alternative promoters and alternative splicing have been found for this gene.
