蛋白名称
B1 bradykinin receptor
免疫原
The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250
特异性
Bradykinin B1 R Monoclonal Antibody detects endogenous levels of Bradykinin B1 R protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor
背景
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
功能
function:This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,
