免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HTR2A
(NP_000612.1)
纯化工艺
Affinity purification
储存
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
背景
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles.
Mutations in this gene are associated with susceptibility to schizophrenia and obsessivecompulsive disorder, and are also associated with response to the antidepressant citalopram
in patients with major depressive disorder (MDD). MDD patients who also have a mutation in
intron 2 of this gene show a significantly reduced response to citalopram as this
antidepressant downregulates expression of this gene. Multiple transcript variants encoding
different isoforms have been found for this gene
