基因名称(Gene Name)
TRIM11 RNF92
免疫原
Synthesized peptide derived from human TRI11 AA range: 128-178
特异性
This antibody detects endogenous levels of TRI11 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq, Jul 2008],
功能
domain:The coiled-coil domain and the B30.2 domain are both necessary for interaction with humanin.,function:May have E3 ubiquitin ligase activity. May contribute to the regulation of the intracellular level of humanin or humanin-containing proteins through the proteasomal degradation pathway.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subunit:Binds cytoplasmic tail of integrin alpha-1. Interacts with the humanin peptide.,tissue specificity:Ubiquitous.,
