免疫原
Synthesized peptide derived from human BIN3 AA range: 184-234
特异性
This antibody detects endogenous levels of BIN3 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008],
功能
function:Involved in cytokinesis and septation where it has a role in the localization of F-actin.,similarity:Contains 1 BAR domain.,tissue specificity:Ubiquitously expressed except in brain.,
