基因名称(Gene Name)
FKBP10 FKBP65 PSEC0056
免疫原
Synthesized peptide derived from human FKB10 AA range: 339-389
特异性
This antibody detects endogenous levels of FKB10 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.[provided by RefSeq, Nov 2009],
功能
catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by both FK506 and rapamycin, but not by cyclosporin A.,function:PPIases accelerate the folding of proteins during protein synthesis.,PTM:Glycosylated and phosphorylated.,similarity:Belongs to the FKBP-type PPIase family.,similarity:Contains 2 EF-hand domains.,similarity:Contains 4 PPIase FKBP-type domains.,
