基因名称(Gene Name)
ATG12 APG12 APG12L
免疫原
Synthesized peptide derived from human ATG12 AA range: 80-130
特异性
This antibody detects endogenous levels of ATG12 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008],
功能
function:Required for autophagy.,similarity:Belongs to the ATG12 family.,subunit:Conjugated to ATG5.,tissue specificity:Ubiquitous.,