基因名称(Gene Name)
NEO1 IGDCC2 NGN
免疫原
Synthesized peptide derived from human NEO1 AA range: 82-132
特异性
This antibody detects endogenous levels of NEO1 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
功能
alternative products:Additional isoforms seem to exist,function:May be involved as a regulatory protein in the transition of undifferentiated proliferating cells to their differentiated state. May also function as a cell adhesion molecule in a broad spectrum of embryonic and adult tissues.,similarity:Belongs to the immunoglobulin superfamily. DCC family.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 6 fibronectin type-III domains.,tissue specificity:Widely expressed and also in cancer cell lines.,
