基因名称(Gene Name)
FAM20C DMP4
免疫原
Synthesized peptide derived from human DMP4 AA range: 328-378
特异性
This antibody detects endogenous levels of DMP4 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a member of the family of secreted protein kinases. The encoded protein binds calcium and phosphorylates proteins involved in bone mineralization. Mutations in this gene are associated with the autosomal recessive disorder Raine syndrome. [provided by RefSeq, Apr 2014],
功能
disease:Defects in FAM20C are the cause of Raine syndrome (RNS) [MIM:259775]. RNS is an autosomal recessive osteosclerotic bone dysplasia with neonatal lethal outcome. Clinical features include generalized osteosclerosis, craniofacial dysplasia and microcephaly.,function:Calcium-binding protein which may play a role in dentin mineralization.,similarity:Belongs to the FAM20 family.,tissue specificity:Widely expressed.,
