免疫原
Synthesized peptide derived from human ADAT1 AA range: 322-372
特异性
This antibody detects endogenous levels of ADAT1 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010],
功能
cofactor:Binds 1 inositol hexakisphosphate (IP6) per subunit.,function:Specifically deaminates adenosine-37 to inosine in tRNA-Ala.,similarity:Belongs to the ADAT1 family.,similarity:Contains 1 A to I editase domain.,tissue specificity:Ubiquitously expressed.,
