免疫原
Synthesized peptide derived from human PTN4 AA range: 496-546
特异性
This antibody detects endogenous levels of PTN4 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008],
功能
catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:May act at junctions between the membrane and the cytoskeleton.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.,similarity:Contains 1 FERM domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
